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The Knowledge Hub is ECNP's central resource for researchers and clinicians in applied neuroscience, featuring educational courses, webinars and podcasts.

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Highlights

Psychedelics and plasticity: from synapses to cognition

This podcast with speakers Linda Simmler, Switzerland, Frederick Barrett, United States, and host Friederike Holze, Switzerland, is part of the Congress Preview podcast series from ECNP.They explore the therapeutic potential of psychedelics like psilocybin, discussing both preclinical and clinical research. Topics include synaptic plasticity, neural circuits, and the role of psychedelics in treating depression, anxiety, and addiction. The conversation highlights key challenges such as establishing causal links between neuroplasticity and therapeutic effects, predicting patient responses, and navigating public perception and funding. Join them for their sym…

Online machine learning school
Online Machine Learning Schoo…

This ECNP course provides comprehensive training on machine learning (ML) methodologies for beginners, tailored specifically to clinical research applications in psychiatry and neuroscience.

Autoimmune causes of mental i…

There are many lines of evidence to suggest that a proportion of psychosis has an autoimmune basis however there have not been any biomarkers to identify individuals that might benefit from immune modifying treatments. This has p…

Prompt engineering for mental…

Prompt engineering is a powerful tool to optimise the use of generative AI in clinical settings, not only in psychiatry. While large language models (LLM) have shown potential across a range of tasks - from data extraction to psy…

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Precision medicine
AI-driven insights into genetics and symptoms in psychiatry

1. Polygenic scores (PGS) are widely used to estimate genetic risk for complex traits, but standard additive methods can miss non-additive effects. This talk introduces the promise and pitfalls of using artificial intelligence (AI) models – specifically, XGBoost and neural netwo…

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New tools in neuroscience applied
Patient and public involvement in neuroscience

Patient and Public Involvement and Engagement (PPIE) and research co-production are rapidly becoming a prerequisite across European funders and regulators. Whilst PPIE is well established in clinical research, adoption has been slower in neuropharmacology and neurotechnology. Th…

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Neurodevelopmental conditions
Evolutionary genomics in autism spectrum disorder

Why does a neurodevelopmental condition such as Autism Spectrum Disorder (ASD), which is associated with reduced reproductive fitness, remainprevalent in human populations? This presentation addresses this paradox by applying advanced evolutionary genomics approaches to the larg…

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Neuroimaging
Indirect effects of weight gain on cortical thinning

Individuals with bipolar disorder (BD) are at heightened risk for obesity, a condition linked to neuroanatomical changes such as hippocampal atrophy and cortical thinning. In our previous  longitudinal study we saw that weight gain was associated with hippocampal atrophy, w…

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Artificial Intelligence and computational models
Prompt engineering for mental health

Prompt engineering is a powerful tool to optimise the use of generative AI in clinical settings, not only in psychiatry. While large language models (LLM) have shown potential across a range of tasks - from data extraction to psychotherapy - their clinical utility hinges on how …

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Psychedelics
Psychedelics and plasticity: from synapses to cognition

This podcast with speakers Linda Simmler, Switzerland, Frederick Barrett, United States, and host Friederike Holze, Switzerland, is part of the Congress Preview podcast series from ECNP.They explore the therapeutic potential of psychedelics like psilocybin, discussing both precl…

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Digital Health
Electronic health records to characterise the prodromes

Understanding the prodrome to severe mental disorders is critical for prevention. Understanding their nature (duration, symptom evolution and presentation) is essential for early detection and intervention. Much of the existing knowledge is based on “look-back” interviews and sm…

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Digital Health
Digital phenotyping of mood episodes in bipolar disorder

Anticipating mood episodes in patients with bipolar disorder (BD) is a critical challenge, with digital phenotyping holding significant promise as a tool for early detection. This talk will explore different methodological approaches to predicting emerging mood episodes in patie…

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Trauma and stress-related disorders
Loss and grief among war-affected children

Title: Loss and grief among war-affected childrenSpeaker: Christopher Layne, USA, and Iryna Raspopina, UkraineOutline: This webinar will provide a comprehensive overview of the impact of war-related bereavement and losses on children and adolescents, highlighting both the advers…

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Pharmacogenomics
Accelerated aging in mental disorders

This webinar was recorded on 18 July 2025 as part of the Pharmacogenomics webinar series.Title: Severe mental disorders and accelerated biological agingSpeaker: Claudia Pisanu, ItalyOutline: Severe mental disorders such as bipolar disorder, major depressive disorder and schizoph…

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