Depression: state-of-the-art and future directions in research and treatment (In-depth)

This ECNP course provides a state-of-the-art overview of prevention and treatment strategies to reduce the impact of depression in our society.

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Description

This course aims to provide a state-of-the-art overview of prevention and treatment strategies to reduce the impact of depression in our society. For this, it is essential to learn about preclinical and clinical research activities and developments that are ongoing to further advance the development of (novel) prevention and treatment strategies. By providing 8 biweekly lectures by experts on the concept of depression, the etiology of depression and on key current and emerging prevention and treatment strategies of depression, this course will update junior scientists and clinicians of developments in the field. After this course, students will have a more comprehensive understanding of current and emerging topics in the fields of depression research and how these impact prevention and treatment strategies.

This course is organised by the ECNP Depression Meta-Network, with Brenda Penninx and Andreas Reif as principal organisers.

Learning objectives

  1. To realise the public health impact of depression, its heterogeneity and its transdiagnostic relevance.  
  2. To understand the multi-component and complex aetiology of depression and how this is relevant in shaping precision medicine approaches for depression.
  3. To understand (the state-of-the art evidence) of treatment of depression and what new developments are to be expected in the future. 

Audience

Early-career clinical or preclinical researchers and clinicians (holding an MSc or MD), with an interest in depression research and treatment. 

Course format

This in-depth track offers a comprehensive learning experience, combining self-paced and interactive elements:

  • Ten 30-minute video lectures, available to watch at your own convenience
  • Embedded knowledge tests within each lecture
  • Pre-course and post-course tests to assess your understanding at the beginning and end of the course
  • Six live online sessions with course lecturers
  • A group assignment to apply your knowledge
  • An in-person Colloquium on 10 October in Amsterdam, Netherlands for deeper engagement and networking

To successfully complete the in-depth track, participants must:

  • Watch all lectures
  • Complete all knowledge tests
  • Attend at least 4 of the 6 live sessions
  • Attend the in-person Colloquium on 10 October in Amsterdam
  • Complete the group assignment

Prefer a lighter option and/or unable to attend the Colloquium? You can register for the on-demand track, which includes access to the video lectures and knowledge tests, and can be completed entirely at your own pace.

Course schedule

Lecture 1A - Introduction to depression: Current state of depression treatment (Andreas Reif, Germany) – Released 21 July 2025

Lecture 1B - Introduction to depression: Phenomenology, prevalence and impact (Brenda Penninx, The Netherlands) – Released 21 July 2025

Live session 1 – 1 September 16.00 CET

Lecture 2 - Pre-clinical models of depressive neurobehavioral states (Christopher Pryce, Switzerland) – Released 2 September 2025

Lecture 3 - (Epi)Genetics and neurobiology of depression (Elisabeth Binder, Germany) – Released 2 September 2025

Live session 2 – 22 September 16.00 CET

Colloquium Amsterdam – 10 October 14.30-19.30 – in-person

Lecture 4 - Environmental risk and resilience factors in depression (Christiaan Vinkers, The Netherlands) – Released 13 October 2025

Lecture 5 - Psychological treatments and depression impact (Pim Cuijpers, The Netherlands) – Released 13 October 2025

Live session 3 – 3 November 16.00 CET

Lecture 6 - Psychedelics and depression (Gitte Knudsen, Denmark) – 4 November 2025

Lecture 7 - Brain stimulation (rTMS, ECT, DBS) and depression (Jonathan Repple, Germany) – 4 November 2025

Live session 4 – 24 November 16.00 CET

Lecture 8 - Nutrition, microbiome and depression (John Cryan, Ireland) – 25 November 2025

Lecture 9 - Digital health intervention and depression (Inez Germeys, Belgium) – 25 November 2025

Live session 5 – 15 December 16.00 CET

Live session 6 – student presentations – 12 January 2026

How to enrol

Application to this course is available to all individuals with a myECNP account. If you do not yet have a myECNP account, please visit the ECNP website at ecnp.eu and navigate to the ‘myECNP’ tab.

  • Application deadline: 3 July 2025
  • Notification of acceptance: Before 21 July 2025
  • Application requirements: A brief motivation statement and a short CV

Should you have any questions, please feel free to contact us at knowledge-hub@ecnp.eu.

Faculty

Andreas Reif

Course organiser/speaker

University Hospital Frankfurt | Germany

Brenda Penninx

Course organiser/speaker

Amsterdam UMC | The Netherlands

Christopher Pryce

Speaker

University of Zurich | Switzerland

Elisabeth Binder

Speaker

Max Planck Institute for Psychiatry | Germany

Christiaan Vinkers

Speaker

Amsterdam UMC | The Netherlands

Pim Cuijpers

Speaker

VU University Amsterdam | The Netherlands

Gitte Knudsen

Speaker

Copenhagen University Hospital | Denmark

Jonathan Repple

Speaker

Goethe University Frankfurt | Germany

John Cryan

Speaker

University College Cork | Ireland

Inez Germeys

Speaker

KU Leuven | Belgium

Faculty

Andreas Reif

Course organiser/speaker

University Hospital Frankfurt | Germany

Brenda Penninx

Course organiser/speaker

Amsterdam UMC | The Netherlands

Christopher Pryce

Speaker

University of Zurich | Switzerland

Elisabeth Binder

Speaker

Max Planck Institute for Psychiatry | Germany

Christiaan Vinkers

Speaker

Amsterdam UMC | The Netherlands

Pim Cuijpers

Speaker

VU University Amsterdam | The Netherlands

Gitte Knudsen

Speaker

Copenhagen University Hospital | Denmark

Jonathan Repple

Speaker

Goethe University Frankfurt | Germany

John Cryan

Speaker

University College Cork | Ireland

Inez Germeys

Speaker

KU Leuven | Belgium