Description
This course aims to provide a state-of-the-art overview of prevention and treatment strategies to reduce the impact of depression in our society. For this, it is essential to learn about preclinical and clinical research activities and developments that are ongoing to further advance the development of (novel) prevention and treatment strategies. By providing 8 biweekly lectures by experts on the concept of depression, the etiology of depression and on key current and emerging prevention and treatment strategies of depression, this course will update junior scientists and clinicians of developments in the field. After this course, students will have a more comprehensive understanding of current and emerging topics in the fields of depression research and how these impact prevention and treatment strategies.
This course is organised by the ECNP Depression Meta-Network, with Brenda Penninx and Andreas Reif as principal organisers.
Learning objectives
- To realise the public health impact of depression, its heterogeneity and its transdiagnostic relevance.
- To understand the multi-component and complex aetiology of depression and how this is relevant in shaping precision medicine approaches for depression.
- To understand (the state-of-the art evidence) of treatment of depression and what new developments are to be expected in the future.
Audience
Early-career clinical or preclinical researchers and clinicians (holding an MSc or MD), with an interest in depression research and treatment.
Course format
This in-depth track offers a comprehensive learning experience, combining self-paced and interactive elements:
- Ten 30-minute video lectures, available to watch at your own convenience
- Embedded knowledge tests within each lecture
- Pre-course and post-course tests to assess your understanding at the beginning and end of the course
- Six live online sessions with course lecturers
- A group assignment to apply your knowledge
- An in-person Colloquium on 10 October in Amsterdam, Netherlands for deeper engagement and networking
To successfully complete the in-depth track, participants must:
- Watch all lectures
- Complete all knowledge tests
- Attend at least 4 of the 6 live sessions
- Attend the in-person Colloquium on 10 October in Amsterdam
- Complete the group assignment
Prefer a lighter option and/or unable to attend the Colloquium? You can register for the on-demand track, which includes access to the video lectures and knowledge tests, and can be completed entirely at your own pace.
Course schedule
Lecture 1A - Introduction to depression: Current state of depression treatment (Andreas Reif, Germany) – Released 21 July 2025
Lecture 1B - Introduction to depression: Phenomenology, prevalence and impact (Brenda Penninx, The Netherlands) – Released 21 July 2025
Live session 1 – 1 September 16.00 CET
Lecture 2 - Pre-clinical models of depressive neurobehavioral states (Christopher Pryce, Switzerland) – Released 2 September 2025
Lecture 3 - (Epi)Genetics and neurobiology of depression (Elisabeth Binder, Germany) – Released 2 September 2025
Live session 2 – 22 September 16.00 CET
Colloquium Amsterdam – 10 October 14.30-19.30 – in-person
Lecture 4 - Environmental risk and resilience factors in depression (Christiaan Vinkers, The Netherlands) – Released 13 October 2025
Lecture 5 - Psychological treatments and depression impact (Pim Cuijpers, The Netherlands) – Released 13 October 2025
Live session 3 – 3 November 16.00 CET
Lecture 6 - Psychedelics and depression (Gitte Knudsen, Denmark) – 4 November 2025
Lecture 7 - Brain stimulation (rTMS, ECT, DBS) and depression (Jonathan Repple, Germany) – 4 November 2025
Live session 4 – 24 November 16.00 CET
Lecture 8 - Nutrition, microbiome and depression (John Cryan, Ireland) – 25 November 2025
Lecture 9 - Digital health intervention and depression (Inez Germeys, Belgium) – 25 November 2025
Live session 5 – 15 December 16.00 CET
Live session 6 – student presentations – 12 January 2026
How to enrol
Application to this course is available to all individuals with a myECNP account. If you do not yet have a myECNP account, please visit the ECNP website at ecnp.eu and navigate to the ‘myECNP’ tab.
- Application deadline: 3 July 2025
- Notification of acceptance: Before 21 July 2025
- Application requirements: A brief motivation statement and a short CV
Should you have any questions, please feel free to contact us at knowledge-hub@ecnp.eu.
Faculty
Andreas Reif
Course organiser/speaker
University Hospital Frankfurt | Germany

Andreas Reif
Course organiser/speaker
University Hospital Frankfurt | Germany
Brenda Penninx
Course organiser/speaker
Amsterdam UMC | The Netherlands

Brenda Penninx
Course organiser/speaker
Amsterdam UMC | The Netherlands
Christopher Pryce
Speaker
University of Zurich | Switzerland

Christopher Pryce
Speaker
University of Zurich | Switzerland
Elisabeth Binder
Speaker
Max Planck Institute for Psychiatry | Germany

Elisabeth Binder
Speaker
Max Planck Institute for Psychiatry | Germany
Christiaan Vinkers
Speaker
Amsterdam UMC | The Netherlands

Christiaan Vinkers
Speaker
Amsterdam UMC | The Netherlands
Pim Cuijpers
Speaker
VU University Amsterdam | The Netherlands

Pim Cuijpers
Speaker
VU University Amsterdam | The Netherlands
Gitte Knudsen
Speaker
Copenhagen University Hospital | Denmark

Gitte Knudsen
Speaker
Copenhagen University Hospital | Denmark
Jonathan Repple
Speaker
Goethe University Frankfurt | Germany

Jonathan Repple
Speaker
Goethe University Frankfurt | Germany
John Cryan
Speaker
University College Cork | Ireland

John Cryan
Speaker
University College Cork | Ireland
Inez Germeys
Speaker
KU Leuven | Belgium

Inez Germeys
Speaker
KU Leuven | Belgium
Faculty
Andreas Reif
Course organiser/speaker
University Hospital Frankfurt | Germany

Andreas Reif
Course organiser/speaker
University Hospital Frankfurt | Germany
Brenda Penninx
Course organiser/speaker
Amsterdam UMC | The Netherlands

Brenda Penninx
Course organiser/speaker
Amsterdam UMC | The Netherlands
Christopher Pryce
Speaker
University of Zurich | Switzerland

Christopher Pryce
Speaker
University of Zurich | Switzerland
Elisabeth Binder
Speaker
Max Planck Institute for Psychiatry | Germany

Elisabeth Binder
Speaker
Max Planck Institute for Psychiatry | Germany
Christiaan Vinkers
Speaker
Amsterdam UMC | The Netherlands

Christiaan Vinkers
Speaker
Amsterdam UMC | The Netherlands
Pim Cuijpers
Speaker
VU University Amsterdam | The Netherlands

Pim Cuijpers
Speaker
VU University Amsterdam | The Netherlands
Gitte Knudsen
Speaker
Copenhagen University Hospital | Denmark

Gitte Knudsen
Speaker
Copenhagen University Hospital | Denmark
Jonathan Repple
Speaker
Goethe University Frankfurt | Germany

Jonathan Repple
Speaker
Goethe University Frankfurt | Germany
John Cryan
Speaker
University College Cork | Ireland

John Cryan
Speaker
University College Cork | Ireland
Inez Germeys
Speaker
KU Leuven | Belgium

Inez Germeys
Speaker
KU Leuven | Belgium