2025

This webinar was recorded on 2 September 2025 as part of the PsychX webinar series.Title: From Cradle to Grave: Integrating Genetic, Family, and Environmental Factors in Mood Disorder TreatmentSpeaker: Andreas Reif, GermanyOutline: This lecture explores how the treatment of mood…

Title: Dopaminergic therapy for inflammation-related anhedonia in depressionSpeaker: Jennifer Felger, USAOutline: Inflammation is increased ~1/3 of patients with depression and has been associated with poor response to conventional antidepressants. A large literature has establi…

Childhood trauma is a major risk factor for adult psychiatric and physical disorders, with recent research indicating these effects may extend across generations. We investigate the molecular basis of the long-term effects and intergenerational transmission of trauma. We examine…

The Nordic countries have a long tradition of leveraging universal healthcare data that track individuals from birth to death, providing an unparalleled resource for research. Linking these registers with national biobanks creates a powerful foundation for large-scale psychiatri…

1.  Understanding how genetic factors influence treatment variability is central to precision medicine. Linking genomic data with real-world health records allows the assessment of treatment response at scale. Using longitudinal data from the Estonian Biobank, we examine ho…

1. The talk will cover the results from the recent Psychiatric Genomics Consortium Bipolar Disorder study published in Nature. Specifically, it will focus on the use of community/biobank studies and self-report data in genetic studies of bipolar disorder, and the implications fo…

Title: More or less about 3q29 - dissecting the cellular effects of schizophrenia risk variants, 3q29 del/dup, in neural development and functionSpeaker: Bingqing He, SwedenOutline: Schizophrenia is a severe psychiatric disorder with high heritability, yet its diagnosis and trea…

1. Polygenic scores (PGS) are widely used to estimate genetic risk for complex traits, but standard additive methods can miss non-additive effects. This talk introduces the promise and pitfalls of using artificial intelligence (AI) models – specifically, XGBoost and neural netwo…

Patient and Public Involvement and Engagement (PPIE) and research co-production are rapidly becoming a prerequisite across European funders and regulators. Whilst PPIE is well established in clinical research, adoption has been slower in neuropharmacology and neurotechnology. Th…

Why does a neurodevelopmental condition such as Autism Spectrum Disorder (ASD), which is associated with reduced reproductive fitness, remainprevalent in human populations? This presentation addresses this paradox by applying advanced evolutionary genomics approaches to the larg…