2025

1. Polygenic scores (PGS) are widely used to estimate genetic risk for complex traits, but standard additive methods can miss non-additive effects. This talk introduces the promise and pitfalls of using artificial intelligence (AI) models – specifically, XGBoost and neural netwo…

Patient and Public Involvement and Engagement (PPIE) and research co-production are rapidly becoming a prerequisite across European funders and regulators. Whilst PPIE is well established in clinical research, adoption has been slower in neuropharmacology and neurotechnology. Th…

Why does a neurodevelopmental condition such as Autism Spectrum Disorder (ASD), which is associated with reduced reproductive fitness, remainprevalent in human populations? This presentation addresses this paradox by applying advanced evolutionary genomics approaches to the larg…

Individuals with bipolar disorder (BD) are at heightened risk for obesity, a condition linked to neuroanatomical changes such as hippocampal atrophy and cortical thinning. In our previous  longitudinal study we saw that weight gain was associated with hippocampal atrophy, w…

Prompt engineering is a powerful tool to optimise the use of generative AI in clinical settings, not only in psychiatry. While large language models (LLM) have shown potential across a range of tasks - from data extraction to psychotherapy - their clinical utility hinges on how …

This podcast with speakers Linda Simmler, Switzerland, Frederick Barrett, United States, and host Friederike Holze, Switzerland, is part of the Congress Preview podcast series from ECNP.They explore the therapeutic potential of psychedelics like psilocybin, discussing both precl…

Prof. Michael E. Benros is Director of the Copenhagen Research Centre for Biological and Precision Psychiatry. In their Precision Psychiatry Initiatives, they utilize the wealth of Danish Big Data resources, including nationwide registers, population-based electronic health reco…

Understanding the prodrome to severe mental disorders is critical for prevention. Understanding their nature (duration, symptom evolution and presentation) is essential for early detection and intervention. Much of the existing knowledge is based on “look-back” interviews and sm…

This podcast with guest speaker Alberto Giubilini, United Kingdom, and host Michele De Prisco, Spain, is part of the Brains On Brains podcast series from ECNP. Can AI act as a moral advisor in psychiatry? What consent and equity dilemmas do we face? Should we fear or embrac…

Anticipating mood episodes in patients with bipolar disorder (BD) is a critical challenge, with digital phenotyping holding significant promise as a tool for early detection. This talk will explore different methodological approaches to predicting emerging mood episodes in patie…